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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ece3035f7a274ece0f361c4772a5af52dc8777b1c66883b78fc305f67c0f0a78' 
  AND token = 'e5IRzJ55mYnpnxaDgZ76Z5lu6GVj+u3ThPO6uyDvjk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}