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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c67f0440efbb697b35fadcc66d8476c6aa33b163316090397f9df284bf14d8ae' 
  AND token = 'oDFUS6rdG/G/o47pYXxbHzx9dsSt56qiwbqIszCI30M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}