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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd74d68ad3a57e9044c2cbb207fbf1b00bb9d895be64ef74192d2895ac5f43218' 
  AND token = 'w4RIVzj9sCdmMalXNVIjyRwhWHe3vFcs9v5y5oJMjSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}