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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80f543a5b3dc51e0defd97f2bfb387b62f9bf71872c06f03bbe27ed415f733a9' 
  AND token = 'eL98KChj0muNRjJcJBMLZ6uxdL7DYLZSg/Ub9lL8gmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}