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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3c09e449c4bbac78b75949c040f112b8044120e9e7ad7255ccf8adf1e61ee52' 
  AND token = 'J0/7iR++4w0UGwLd2JTXki9JpeV0BAiynzS+Uf+FCgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}