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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ef39434d2be0e41d6dbb2211b39299c81390732f921c8d6d2666d7b70eab907' 
  AND token = '7x/42385xD39/otz766EPIGvcMscg0+S9WsGGErRokE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}