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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cda6f33075a90f134299901f33c1fcaf971374dc1a22809ef061ff666bbaf7f' 
  AND token = 'LVOU0MDtnTmmXmfnCkPYmAHSy7ZtGz5SY/dF31Tcviw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}