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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9efb7a3fd45865409c8a77d661cd25ad0a73c12fb3d2892663f4120ce240c89' 
  AND token = '4ZZ9WDC9U9dff5OfeYgWu+wDIX5Cq6WAvQ/xckA4zF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}