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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654cb8abc877cdeade07556256b2a8c2423b0764df86569921ff4e1d94793142' 
  AND token = 'NjLoTPdDyMmOczHBWdtcaVwrWIMVoV9r6UqHR5N3ga0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}