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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '672ab460c7dd60bfd724b9d17cbca588d0396d43a3572818d0f5c01021baa7e8' 
  AND token = 'EB2T5CGhJcY+776RwW86hHY5LnS6P14Kt7WI/JZK1Lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}