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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c533086d35d27b11df4def627a65cb7ed636bd66f4f60b495e0d1fce163f87aa' 
  AND token = 'nyBtD6iesoMmQogWBU3+gQNLf4O2qt1OYU5dvSy0fnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}