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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71f5fc7e7a3959e33fc46a4a8f35761c72e502641c6231039962870c4b77c033' 
  AND token = '43UWkoTeEVXwYRWby0BSjFXT/bqW0cu4NR5fXks9lOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}