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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67ae6f27d32f9a4548230c15793a78c112e8e995155c52c8324c184aa81dc87b' 
  AND token = 'SWOlz7FAq9//u9ZerX7D0kfPRcIRC9bGNLIKoRzkLeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}