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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fe5bf51d0e8bdff20cf5ef900352268ff47939110c5f31021467383c3bd6601' 
  AND token = 'uNupxOovmg1giE1k8a7jkcwtNGMtqR9VaP9UyW/8pjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}