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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff8e346ed3a7a86f6a2151a7a16c1c9d61f78e5c6274d57b18057dd673af8c97' 
  AND token = '+FSrzU1VfVlP5SvikiiHroOSf27G2agIaAWlGsgUMgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}