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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd397adf4332162c375d053e63961cee8a61626e1327f5d134cdc7fddb5f125f1' 
  AND token = 'nrAeB61mj/i3+bmRTMPk7nRWJjX6dTXg3RFxYODDYq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}