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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a14b80e0f286372a4c52f7668c0be889a347cc6c4240a0a442a9135d0689416' 
  AND token = '109kxEh49KEBQvhoAqeEhYa3RZXKAeQ6t19xRIvsQYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}