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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '241275cb64488c2209501c9db58408a521dcc4ec78fda6b30f05639f541b12f8' 
  AND token = '+nHQBCf+eaITUPrKKJLDUdWyIWD37lUg8LwKT9qHIpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}