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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '444bd77888eb876ed3f7e3b86cfb2182b7e4e88764255ec38013c0a2e38de605' 
  AND token = 'nOXQY824coaSy5MXpVRBgpMgEZHXQbcXYyqcJ2SDwr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}