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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8359379ed3a0dc36168611046f13089702b5e52c01834b95b335ad5af884de44' 
  AND token = 'TuUv00xjkxL9NMiM22pNi36Z/XWeT2Qlu7HW7EGUMt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}