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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '457e50fcc8e3031b48b04d1019b2c91df341c7458d83c509080181d906be8667' 
  AND token = 'Aa44bCUAw6MBjIKA+ROa72PQm40HZACoeJvwG681oE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}