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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '408b143061192e1a11163972ff906d623a07030012a3fd8964a81015970d8d33' 
  AND token = 'eTp21GA9fO9SOc26Iyi1dCN0x7lIhX+/r6NvVUCH/Ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}