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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5257a0ba3a56c36a35bbea8adaebcee169d6a6af59a4b610120c0a53c37a471c' 
  AND token = 'tRinuMGDaAX02EXIE7LUrTsVIS08XyYF55Z3yYzGWAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}