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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '457182b205fade693b57edaa90882734ca19a05c608416af34e54256033872f9' 
  AND token = '0I+CBaWRZI9Y28o2+VCjMe42ebQI8BmBnnOvIYnvccA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}