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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fd3e8ea59a50b5544ec51c4f78110f22a2efe041d0dc12f5c74cce25b470af2' 
  AND token = 'f8KhaE9vby1+wjFjOCofmx5dVVBk+6vGmetjRLxIiKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}