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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f64c120257e5d20aeb96c4527367f704110622a10de8bb821246671855e4e405' 
  AND token = 'WFOTZRqEx/crkoNw4BWc9PimRBFL/0jn9uCJNfI+Pjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}