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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6b7eb9d00645a7e917bf89d8cf150fac34bf5187e304a68faea00b8921d1c34' 
  AND token = 'F4D4NoZBr5zBU5UXCE1JZ5UkMA//rcHYVMbFX3wnc38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}