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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1ca3f44472a909f993570a069ecbdfe4d1fce809720e5be08d7ee07b3c4cae7' 
  AND token = 'pIooLAz6EPUlOy560wG5+H0WO022xZLlUNF1M8sZiac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}