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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e7e7cba1b8eebb51a501f016b91131747da91ea049c5dd265e1e152f6947537' 
  AND token = 'QplRT4nuuQ3qrTEXezNSV2G11vgC0sRkuYB8MRr8AHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}