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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1674ce1281a545906b5086949e37b8322e74bee02c7d18c56a4c704ae7bcca9' 
  AND token = 'v1ETm9zBMgkRWoI9Ep+kE4tWAoRR9gxjTcZsGUfaygU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}