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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f439136081a2c59fb33d7d021faf829d6422379fa06714582a2522a7126f2614' 
  AND token = 'EqSnbXg8P9GhthjsDH6NPKeD6kxtnYHUJdZRE2ImJ2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}