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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '105e31ab6db97cbdf889ef1313dc05c45059f49cb962336841f1b21ac23e9acf' 
  AND token = 'OHzr9UmNW2IG0QCifVwyZG2DFuB0M4c2abBCViQvvCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}