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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '401ba94c9222d2d4d7cfcb8dda518eafe9ce4c7c35a8ff5840b4da1527f9d55d' 
  AND token = 'RT++KXv2hp0Whun74j3qrlpovmb75Elima7qhZmVBmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}