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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f7cf27bad051d29fd5635a6a01d76e87a30c27a27559735c8ed964e9744c050' 
  AND token = 'RQHFC0GslOyIxX0dIJzgp+sHRy5ECUzunoB+oABfHF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}