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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d8fe013f1aa7a335ddefd5a855fa3ec56f450d2824aff1029860e3fedf4c9e9' 
  AND token = 'yIUmJPZDVrq+YEVHm3L4rd1s3yyPD3jYjFvnscxAf54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}