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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eaa17af0a556775b03fffdc3287141fa1066e9e84bc5d154f01fafd65c0380b' 
  AND token = 'TpTO1WJC5OYNwECWnABk9pbSuzZ0o3ILODvOtZm1TMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}