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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afedfabbc00ab098ccabf43729d4099afdfd6a2154884ec095b31ac3dd22ca2a' 
  AND token = 'ocPq3v1Nzh+lAhyU5PoQP9c9wX8EGavqYKN8ZQmzKDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}