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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b468ca9b8cb14e95d97783a0795e00a8afae66fd30f9b511d608d6fe3041bd0' 
  AND token = 'nhBkYZ/ZZnxNlrD3SaTzyhOWqtNnS1RrafPMCFnXkiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}