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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3af943ff95ee7c0b54c54dfbedee92e6aaf7d523fd167213647f6806aa40a80c' 
  AND token = 'lV1jQz7GSI9xhEgAT9O9JcxzYffSsu9/Z8ioV5wL4bQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}