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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f5b86ab6f6dd7f8ca8ae4a9b001b5fd5cf23f76b3d03b49038412a101490bec' 
  AND token = 'LRLnQ8ltfHCWfJrWlJVq/9mTXbvMEwxBxlseaWYso3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}