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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e08770f94affb37d34d71b787ccddb23a6fcffa29df80be438c6d6ae95ef0095' 
  AND token = '5gTdZ2+4jGfMb0ON5Hx0FnwjoJavRZjduvcahGkj4Uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}