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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af0690d0aea49183b60791319b66d1a933d58296c267bb419fbbfed6cb403b07' 
  AND token = 'r5S1xMVMxaaDFPu57McO1joXi5dL2R93lkb8ZcT0Gnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}