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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd70ef9513abb199e83c9b54dd9434003010d971a162331e2a666b47452eeb29c' 
  AND token = 'zPzia3zv+4y5Q//ekSCNgnQmj0WMcvaY5Gsc6p279Wc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}