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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7778c31ce475ca41d0fc2f5f731b5ac86e9fef05f18f7840cc844a7b9db51643' 
  AND token = 'UgHqq8WZELh/noqWY3TCILuxFSG/0r1yrG7ucFOqVOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}