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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df48d0d30e901fde9244adb1b9fd7c1b4f5068c3b7f414ded5276aa7020695de' 
  AND token = 'Fej9ATsdH4KkbS8gzXZe0as378Yj7w5IudtWG6OSiO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}