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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7114b2a1c71649f578d3adf4941f4603e12df895bb0b2d2b66c53b840402703' 
  AND token = 'NIHzc+epEQGyWuk0QEVgsZIIgZKl5QQ+VCPdkr6tgWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}