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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff646c05c4d869a234a201b70b1320e9f184c52f994f027c3f6a62651ffb6166' 
  AND token = '17Rv2UHVAJtdO8HNPeDLyQCniGZ7pw0MNyzyj3SvnAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}