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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbefb4ea98fccb213a5f45ba521c3edecc87668b67ada9a1ccc18c5f9746266a' 
  AND token = 'ICSbs7IhhcLfSZssPo+ngeYUWsuIWkeFjqTsqdOAp7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}