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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2721a9125a0def1cb5e189996f12dab597f4605357ad5c1cab5f9d3ec01e2b4' 
  AND token = 'D0R+m1OV1kYH5Bcoc82MojEeJyjarSS0309z/g35Z3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}