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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae3e9e56d05be0522e62ffbc6267c74fa58e6e358e27b5dfda18d534535ee6b8' 
  AND token = 'V1bdTtDxUT2p3RPWA+Nm6NuwBmGyRkylOwnBJ2Xumcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}